Job Title: Postdoctoral Project Research Scientist – [C Swanton] Cancer Evolution and Genome Instability Laboratory

Details of the role:

Reporting to: Charles Swanton, Principal Investigator, Deputy Clinical Director

Contact term: This is a full-time 2 year position on Crick terms and conditions of employment.

Salary for this Role: From £45,500 with benefits, subject to skills and experience

Application Closing date: 31st of December 2025 at 23.59

About us

The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.

The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We’ve removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy.

About the role

We are looking for a creative and enthusiastic Postdoctoral Project Research Scientist to join the C Swanton Cancer Evolution and Genome Instability Laboratory.

This lab studies how cancers evolve in the body to spread and become resistant to therapy and discovers new ways to treat them more effectively. The research highlights that tumours consist of diverse groups of genetically related cancer cells, some of which adapt to resist treatments like chemotherapy, immunotherapy, radiotherapy, and targeted therapy. This resistance makes recurrent cancers more difficult to treat, particularly in diseases such as lung cancer.

The Project

As a PPRS you will investigate the role of cell lineage upon lung cancer initiation, both in homeostasis and in the context of challenge with non-mutagenic carcinogens. You will seek to understand which cells within the lung are most susceptible to air pollutants and the routes they take to tumourigenesis. By identifying common pathways across different lineages, you will aspire to identify actionable targets suitable for therapeutic intervention to prevent the onset of cancer. Additionally you will contribute to research which is committed to advancing our understanding of the biology of lung tumour evolution.

You will need to have a creative approach to research with wet lab competencies, and encourage applicants with wet and dry lab skills to apply. As Postdocs may lead projects, collaborate across teams and partners, and support PhD students, it is essential yo have strong communication and collaboration skills.

What you will be doing

To be a successful PPRS for this role, you will need:

• To decipher evolutionary mechanisms during lung cancer initiation and progression using data from animal models.

• To employ novel informatics techniques based on evolutionary principles to the analysis of tumour subclonal evolution.

• To understand cancer biology and the relevant literature sufficiently to take own ideas forward as lead author on new projects.

• To work within the informatics team of the TRACERx and TRACERx EVO programs.

• To record all experiments and code in an accurate timely, clearly presented and reproduceable manner

• To contribute to the dissemination of scientific results by means of writing papers for publication and presentations.

Laboratory Operations Assistant - Service Delivery

Reports to: Quadrant Manager (Technical Team Manager) 

Details of the role: This is a full-time, 18-month fixed term post, on Crick terms & conditions.

The working pattern for this role is:

• Mon-Thu8:00-16:15 and
• Friday8:00-16:00

Please note, the interviews will be held in the second half of January.

About us

The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.

The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We’ve removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy.

About the role

We are looking for a Laboratory Operations Assistant to join the Service Delivery Team.

As a member of the Service Delivery team, you will provide essential, routine support for the research and Science Technology Platform (STP) laboratories based at the Crick.

Working closely with our floor and quadrant managers, you’ll take ownership of the day-to-day maintenance of one of our bustling science floors, with opportunities to support other areas across the institute. Your responsibilities will include managing stock, coordinating the removal of laboratory waste, and helping maintain the highest standards of lab organisation. You’ll also play an important role in handling hazardous materials and assisting with chemical inventory and tracking.

This is a highly collaborative position and you’ll be part of a dedicated team of Laboratory Operations Assistants and will regularly interact with researchers, operational staff, and internal service partners. Strong communication and a proactive mindset will help you thrive in this dynamic environment.

If you’re interested in developing a career in laboratory operations, this role offers an excellent pathway. You’ll gain hands-on experience in a world-leading research institute, with the opportunity to grow into more technical operational positions over time.

What you will be doing

As a Laboratory Operations Assistant at the Crick, you will be responsible for:

• Maintaining the organisation and cleanliness of the laboratory areas including the removal of waste.
• Assisting with, or appropriately signposting, general and laboratory queries from Science and other stakeholders, using a variety of communications media (email, Slack etc) to ensure prompt resolution of issues, queries and challenges.
• Stock management of laboratory supplies; including stock checking, updating the online/ electronic stock control book, receiving deliveries and assisting with restocking the store areas. Upholding the chain of custody from the logistics team to the researchers, ensuring cold storage items are stored correctly.
• Manage hazardous materials safely and according to protocols, including preparing hazardous waste for safe disposal.
• Support communal scientific equipment upkeep.

About you

You will bring:

• Minimum of Mathematics, science and English GCSE and/or experience gained in a relevant technical or service provision role
• Basic computer skills, including Microsoft Office. *
• Able to accurately follow work instructions, record information and carry out tasks in a diligent manner.
• A proven ability to work well with a team
• Self-motivated with a flexible approach and a keen eye for detail. Able to work with minimal supervision using own initiative.

• A good communicator, able to deal confidently and diplomatically with a wide range of people at all levels.

• Ability to respond proactively to contacts in immediate area to ensure provision of service to the laboratories. Able to escalate issues as necessary to Quadrant Manager.
• As there is some heavy work involved and manual handling, candidates should be capable of daily porterage duties. The role requires walking around a large facility covering several floors. *

Minimum criteria *

Job Title: Facilities Management Operations Analyst (CAFM & Ops)

Details of the role:

Working pattern: This is a full time permanent hybrid (4 days a week onsite) role on Crick terms and conditions of employment.

Salary: From £43,000 with benefits, subject to skills and experience

Application Closing Date: 18th of December 2025 at 23.59

About us  

The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.

The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We’ve removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy.

About the role

We are seeking an experienced and methodical Facilities Management Operations Analyst (CAFM & Ops) known internally as CAFM and Ops Performance Analyst, to join us here at the Francis Crick Institute.

This role will be a key part of the facilities team whose objective is to ensure that scientific research does not get disrupted due to building operational matters.

You will play a key role overseeing asset management and maintenance scheduling through our CAFM system (Planon), keeping operations efficient and uninterrupted.

You’ll use the CAFM system to monitor performance, produce KPI dashboards, and drive process improvements and system upgrades.

This is a pivotal role where your work will safeguard and strengthen the environment that enables ground breaking discoveries.

What you will be doing

At the Crick, you will:

• Be an operational owner and system administrator for the Crick’s CAFM system (Planon)

• Provide Management information to Department Heads and Service Leads, extract and manipulate data from the building systems, develop and build reports in line with user bespoke requirements using available IT tools. Develop and measure KPIs across building services functions, create dashboards to enable clear communication and monitoring of performance trends, ensuring relevant statutory and regulatory compliance is captured.

• Maintain the Planon system to ensure the Crick CAFM system remains at optimal performance and is fully supported.

• Identify, develop and manage continual improvements (including system version upgrades) to the CAFM system

• Support site audits of building and science equipment to ensure all recorded asset data is current and accurate.

Workday Enterprise Systems Manager

Details of the role

Working pattern: Monday – Friday: This is a full time permanent hybrid role on Crick terms and conditions of employment.

Salary: From £60,805 with benefits, subject to skills and experience

Application closing date: 4th of January 2026 at 11.59pm

About us

The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.

The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We’ve removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy.

Join Us as a Workday Enterprise Systems Manager!

Are you a Senior Workday Developer or Technology Lead looking for your next big challenge? Passionate about driving value through cutting-edge enterprise technology? If so, we’ve got an exciting opportunity that could be the perfect next step in your career.

We're looking for a Workday Enterprise Systems Manager to join the team and play a pivotal role within the IT Operations team, to ensure that Workday continues to provide value and ROI. You will take ownership of Workday platforms and shape its future, whilst delivering real impact, leading innovation and transforming how our organisation works.

You'll also have the opportunity to build custom applications and create impactful proofs of concept (PoCs) that drive real innovation across the business whilst also having the opportunity to focus on innovation, including development of automation and AI, which is key to this role.

As a Workday Enterprise Systems Manager, you will be joining a team of enterprise systems colleagues working across functions to manage and enhance how Workday supports organisational processes and customer experience for colleagues. You will have the change to collaborate with other members of the ITO team, as well as the People and Finance team and beyond.

What you will be doing

As a Workday Enterprise Systems Manager at the Crick, you will:

• Ensure Workday alignment with business needs and priorities, and IT strategic objectives (collaborating with colleagues in IT Operations (ITO) People and Finance) by capturing, assessing and prioritising improvements across People and Finance, ensuring agile sprints are delivered on time, within scope, and budget in line with business objectives. Manage competing demands from.

• Manage all aspects of the implementation, configuration, and optimisation of all Workday modules working with cross-functional colleagues to create the detailed designs, define technical specifications, and develop delivery plans.

• Ensure robust development practices, including coding standards, testing, and documentation, are following and continuously improved through regular lessons learned/ retrospective exercises, e.g. in accordance with ITIL best practices. Awareness of GDPR, considering and managing related risks.

• Monitor health, usage, and overall compliance of Workday and its applications

• Create and / or maintain internal technical documentation and manuals with regards to Workday processes and automation tasks

• Monitor and resolve escalated BAU issues, providing advanced technical troubleshooting, root cause analysis, and continuous improvement.

About you

You will bring

• Strong hands-on Workday development and configuration experience in one or more modules (e.g., HCM, Core HR, Financials, Absence, Security, Integrations) including using AI and automation. Solid understanding of business processes in.*

• Demonstrable experience in system integration, platform development, and change delivery in an enterprise context. Knowledge of large-scale data uploads.*

• Workday Security Model: Experience managing domains, security groups, and role-based access controls.

• Workday Integrations: Proficiency with EIBs, Core Connectors, Workday Web Services (WWS). API & Web Services: Understanding of REST/SOAP APIs, JSON, and XML for integration work.*

• Change Control & QA: Experience with peer reviews, structured testing, deployment practices, and environment management.

• Familiarity with Agile or iterative delivery methods.*

• Benchmarking & Innovation: Awareness of Workday roadmap, emerging features, and innovation opportunities.*

*Minimum Requirements

About Working at the Crick

Our values  

Everyone who works at the Crick has a valuable role to play in advancing the Crick’s mission and shaping our culture

• We are

  bold. We make space for creative, dynamic and imaginative ideas and approaches. We’re not afraid to do things differently.

• We are

  open. We’re highly collaborative and interactive, and make sure our activities are visible to the outside world.

• We are

  collegial. We show respect for one another, work cooperatively and support the wider community.

Job Title: Research Management Administration Officer (Scientific Discourse)

Details of the role:

Working pattern: Monday – Friday. Peak activity during recruitment cycles may require occasional early starts, evenings or short periods of flexible working. This is a full-time, hybrid (3 days a week) permanent position on Crick Terms and Conditions of Employment

Salary: From £45,350 with benefits, subject to skills and experience

Application closing date: 11th of January at 23.59

About us

The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.

The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We’ve removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy.

About the role

We are looking for an organised and pro-active Research Management Administration Officer to join our Research Management support team.

This role plays a vital role in sustaining the Crick’s scientific culture by leading lectures, seminars, symposia, and other key events that showcase diverse scientific exchange.

Working closely with the Assistant Research Director and Communications team, you’ll ensure these activities are effectively planned, delivered, and promoted. You’ll take ownership of discourse events end to end, while contributing to faculty retreats and advisory board meetings. The role also supports group leader recruitment, coordinating symposia, interviews, and candidate visits to integrate them into the wider programme of scientific dialogue.

We’re looking for someone with strong event experience, a passion for science, and ideally some recruitment knowledge, who can build relationships, bring energy, and deliver world class events.

What you will be doing

As a Research Management Officer at the Crick, you will:

Scientific discourse

• Lead the Crick’s scientific discourse activities, including Crick Lectures, Insight Lectures, Annual Science Meeting, Annual Technology Meeting, Medicine at the Crick, Interest Groups and Crick Conferences.

• Coordinate invitations, logistics, scheduling, itineraries, publicity, travel, and on-the-day delivery for high-profile speakers and events.

• Coordinate and work closely with committees responsible for discourse (e.g. Lecture Committee, ASM Committee, Conferences Committee), working closely with the ARD for Scientific Discourse.

• Maintain an integrated events calendar to ensure coherence and diversity of speakers and disciplines, and track expenditure against discourse budget codes (the postholder is not a budget holder).

Group leader recruitment

• Support and coordinate group leader recruitment symposia, chalk talks, and interview events, ensuring professional delivery and strong faculty engagement.

• Assist with candidate itineraries for seminar and chalk talk visits, reimbursements and visitor experience.

• Support onboarding of successful candidates with a focus on integration into the Crick’s scientific community and discourse culture.

Job Title: Enterprise Systems Lead – ServiceNow (Mat cover)

Details of the role:

Working pattern: Monday – Friday. This is a 12 month (Mat cover) fixed term position on Crick terms and conditions of employment. This role is hybrid and requires a minimum of 3 days per week in the office.

Salary: From £59,700 with benefits, subject to skills and experience

Application closing date: 4th of January 2026 at 23.59

About us  

The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.

The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We’ve removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy.

About the role

We are looking for an engaging and passionate Enterprise Systems Lead – Service now to join our team here at the Crick. This is a pivotal role where you will participate in the design, development, and ongoing improvement of enterprise platforms and integrated systems that support the Crick’s needs and ambitions.

You will be a proactive leader with strong organisational skills, stakeholder engagement experience, and a solid understanding of the design and development lifecycle. You’ll bring hands on experience with ServiceNow or similar ITSM platforms, guiding developers and driving process improvements. As this role involves significant project management, you will bring energy and creativity to foster positive team collaboration. You will be a strong listener who takes the time to understand stakeholder needs and effectively translate them into clear actions for the team.

What you will be doing

You will:

• Leading the delivery of design, implementation and service transition for products and services using the current enterprise systems platforms (focused on ServiceNow, but may also include Workday, particularly where scope includes both platforms)

• Working with other leads within ITO to prioritise work packages for the Enterprise systems team

• Working with Application Owners and external vendors to design and support workflows to support operations and science processes.

• Supporting the Head of Enterprise Systems to develop processes and ways of working that support the strategic vision of ITO including automation, documentation, modularisation and reuse.

• Implement integration solutions that connect various enterprise applications and systems.

• Utilise ServiceNow integrations platform (e.g. Flow Designer) to create, streamline, and automate processes.